Article
Role of polymorphic loci in HLA-region rs2647012 and rs805288 in the development of non-Hodgkin's malignant lymphomas in Western Siberia.
Bulletin of experimental biology and medicine - 1 Jun 2014
Weiner A S, Berezina O V, Ovchinnikov V S, Surovtseva M N, Voropaeva E N, Pospelova T I, Filipenko M L
Abstract excerpt
The data of genome-wide association analysis suggest that human 6p21.3 chromosomal region (localization of HLA genes) contains polymorphic loci influencing the risk of developing non-Hodgkin's lymphomas. We analyzed association of rs2647012 and rs805288 loci with the risk for non-Hodgkin's malignant lymphomas in the population of Western Siberia. Allele and genotype frequencies were determined in the group of 298...
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