Article

Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway

2023-05-23

Abstract excerpt

<title>Abstract</title> <p>Keloids are benign fibroproliferative skin tumors caused by aberrant wound healing that can negatively impact patient quality of life. The lack of animal models has limited research on pathogenesis or developing effective treatments, and the etiology of keloids remains unknown. Here, we found that the characteristics of stem cells from keloid lesions and the surrounding dermis differ fr...

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Literature Corpus work: 5c82c889-ce27-5bbe-9bc7-dcd063a811f5
DOI: 10.21203/rs.3.rs-2515946/v1

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