Article
Rs4265085 in GPER1 gene increases the risk for unexplained recurrent spontaneous abortion in Dai and Bai ethnic groups in China.
Reproductive biomedicine online - 1 Apr 2017
Tang Liang, Zheng Shui, Wang Yan, Li Fang, Bao Meihua, Zeng Jie, Xiang Ju, Luo Huaiqing, Li Jianming
Abstract excerpt
Oestrogen receptors are implicated in the pathogenesis of recurrent spontaneous abortion (RSA). Non-genomic oestrogen responses can be mediated by GPER. The prevalence of polymorphisms in GPER1 gene in RSA was assessed in 747 Chinese women from Yunnan province (171 Bai, 258 Chinese Han, 234 Dai, 33 Achang and 51 Jingpo patients). Snapshot technology was used for genotyping the polymorphisms of the GPER1 gene. The...
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