Article
The effects of DICER1 and DROSHA polymorphisms on susceptibility to recurrent spontaneous abortion.
Journal of clinical laboratory analysis - 1 Mar 2020
Ghasemi Marzieh, Rezaei Mahnaz, Yazdi Atefeh, Keikha Narjes, Maruei-Milan Rostam, Asadi-Tarani Mina, Salimi Saeedeh
Abstract excerpt
BACKGROUND: Recurrent spontaneous abortion (RSA) is a serious problem in pregnancy. The exact etiology of RSA is unknown in more than 50% of all the patients. However, genetic variations are known as susceptibility factors for idiopathic RSA. Considering the role of miRNA biosynthesis machinery in the miRNA production and effect of miRNAs on various diseases, this study aimed to evaluate the effects of DICER1...
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