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Article

The role of NLRP3, AIM2, and IFI16 gene polymorphisms in periodontitis susceptibility: a case control study.

BMC oral health - 3 Feb 2026

Saka Nurbanu, Yılmaz Özlem Özge, Tacal Aslan Beste, Öztürk Özener Hafize

Abstract excerpt

BACKGROUND: Polymorphisms in inflammasome genes can modulate the host immune response and influence individual susceptibility to periodontitis. The present study was designed to investigate the association between polymorphisms in NLRP3, AIM2, and IFI16 genes and periodontitis. METHODS: This case control study was conducted among a total of 240 participants, consisting of 80 periodontally healthy (Group H), 80...

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Source

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Identifiers

PMID: 41634660
DOI: 10.1186/s12903-026-07740-w
PMCID: PMC12954921

Genes

NLRP3
AIM2
IFI16
PC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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