Article
The role of NLRP3, AIM2, and IFI16 gene polymorphisms in periodontitis susceptibility: a case control study.
BMC oral health - 3 Feb 2026
Saka Nurbanu, Yılmaz Özlem Özge, Tacal Aslan Beste, Öztürk Özener Hafize
Abstract excerpt
BACKGROUND: Polymorphisms in inflammasome genes can modulate the host immune response and influence individual susceptibility to periodontitis. The present study was designed to investigate the association between polymorphisms in NLRP3, AIM2, and IFI16 genes and periodontitis. METHODS: This case...
Topics
- Humans
- NLR Family, Pyrin Domain-Containing 3 Protein
- Case-Control Studies
- DNA-Binding Proteins
- Female
- Nuclear Proteins
- Genetic Predisposition to Disease
- Male
- Phosphoproteins
- Adult
- Periodontitis
- Polymorphism, Single Nucleotide
- Genotype
- Middle Aged
- Polymorphism, Genetic
- Gene Frequency