Article
Single nucleotide polymorphisms, haplotype association and tumour expression of the vascular endothelial growth factor (VEGF) gene with lung carcinoma.
Gene - 15 Apr 2017
Naykoo Niyaz A, Dil-Afroze, Rasool Roohi, Shah Sonaullah, Ahangar A G, Bhat Imtiyaz A, Qasim Iqbal, Siddiqi Mushtaq A, Shah Zafar A
Abstract excerpt
VEGF contains several polymorphic sites known to influence its expression. We examined the possible association between+405(-634)C>G,+936C>T,-2578C>A and lung cancer in 199 Kashmiri patients and 401 healthy controls. VEGF+405CG,+936CT+TT and-2578CA genotypes were significantly associated with lun...
Topics
- Adenocarcinoma
- Adult
- Aged
- Carcinoma, Squamous Cell
- Case-Control Studies
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Lung Neoplasms
- Male
- Middle Aged