Article
Single nucleotide polymorphisms, haplotype association and tumour expression of the vascular endothelial growth factor (VEGF) gene with lung carcinoma.
Gene - 15 Apr 2017
Naykoo Niyaz A, Dil-Afroze, Rasool Roohi, Shah Sonaullah, Ahangar A G, Bhat Imtiyaz A, Qasim Iqbal, Siddiqi Mushtaq A, Shah Zafar A
Abstract excerpt
VEGF contains several polymorphic sites known to influence its expression. We examined the possible association between+405(-634)C>G,+936C>T,-2578C>A and lung cancer in 199 Kashmiri patients and 401 healthy controls. VEGF+405CG,+936CT+TT and-2578CA genotypes were significantly associated with lung cancer risk compared to VEGF+405CC,+936CC and-2578AA+CC genotypes [OR=0.07 (0.04-0.13), P<0.0001, OR=0.36...
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