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Article

ADIPOQ and LEP variants on asthma and atopy: Genetic association modified by overweight.

Gene - 20 May 2021

Santos Coelho Raísa, Paula Castro Melo Ana, Dos Santos Silva Hátilla, De Cassia Ribeiro Silva Rita, Maria Alvim Matos Sheila, Lima Barreto Maurício, Maria Alcântara-Neves Neuza, Alexandrina Viana de Figueiredo Camila, do Santos Costa Ryan

Abstract excerpt

BACKGROUND: Asthma and atopy are considered condition associated with obesity, being affected by genetic and environmental factors. The LEP and ADIPOQ genes, responsible for the expression and secretion of leptin and adiponectin, respectively, and polymorphisms in such genes have been linked to both diseases, independently, and also with the obesity-associated asthma phenotype in populations with high European...

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Source

Identifiers

PMID: 33631239
DOI: 10.1016/j.gene.2021.145540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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