Article
Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Feb 2017
Guo Xin, Dong Zhiming, Yamada Sohsuke, Li Yuanyuan, Guo Yanli, Shen Supeng, Liang Jia, Tanimoto Akihide, Guo Wei
Abstract excerpt
OBJECTIVE: In the present study, we investigated the relationship between the single-nucleotide polymorphism (SNP) of caspase-3 rs1049216 (C > T), a miRNA target site, and the risk and progression of cervical cancer. MATERIALS AND METHODS: Using polymerase chain reaction-restriction fragment length polymorphism, we evaluated the genotype and distribution of caspase-3 rs1049216 in 515 patients with cervical...
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