Article
Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus.
Acta diabetologica - 1 May 2017
Assmann Taís S, Duarte Guilherme C K, Brondani Letícia A, de Freitas Pedro H O, Martins Égina M, Canani Luís H, Crispim Daisy
Abstract excerpt
AIMS: Type 1 diabetes mellitus (T1DM) is characterized by severe autoimmune destruction of pancreatic beta-cells. The triggering of autoimmunity against beta-cells is probably caused by a combination of environmental and genetic risk factors. Even though much is known about the genetic of T1DM, more information is needed to completely unravel this tangled disease. MicroRNAs (miRNAs) are a class of small noncoding...
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