Article
MicroRNA genes.
Annals of the New York Academy of Sciences - 1 Dec 2008
Zhou Li, He Hongzhi, Mi Jenny X, Li Changgui, Lee Byung, Mi Qing-Sheng
Abstract excerpt
Human type 1 diabetes (T1D) is a chronic autoimmune disorder with complex genetic inheritance. To date, more than 19 insulin-dependent diabetes mellitus (IDDM) susceptibility loci have been mapped to specific chromosome regions in the human. MicroRNAs (miRNAs) are a recently discovered class of evolutionarily conserved small noncoding RNAs that negatively regulate the expression of protein-coding genes without...
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