Article
Association of miR-146a rs2910164 and miR-149 rs2292832 Variants with Susceptibility to Type 2 Diabetes.
Clinical laboratory - 1 Aug 2016
Alipoor Behnam, Meshkani Reza, Ghaedi Hamid, Sharifi Zohreh, Panahi Ghodratollah, Golmohammadi Taghi
Abstract excerpt
BACKGROUND: The deregulation of miRNAs has been implicated in the pathogenesis of type 2 diabetes (T2D). Single nucleotide polymorphisms (SNPs) located within the miRNA sequence could alter miRNA maturation and expression or change the binding affinity of miRNAs to their target mRNAs. In the present study we aimed to elucidate the possible association between the miR-146a rs2910164 and miR-149 rs2292832 variants...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
