Increased expression of microRNA miR‐326 in type 1 diabetic patients with ongoing islet autoimmunity

Abstract excerpt

BACKGROUND: The current paradigm that microRNAs represent a new layer of gene regulation has generated much interest in this field. MicroRNAs have emerged as important regulatory factors involved in the developmental processes and in the regulation of insulin secretion and signalling. Furthermore, recent studies revealed an altered microRNA profiling in lymphocytes of patients with autoimmune diseases like...

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