Article
Association of Osteopontin Gene Polymorphisms with Colorectal Cancer.
Cancer investigation - 7 Feb 2017
Kamal Asmaa, Darwish Rania Kamal, Saad Samar, Salama Mohamed, El-Baradie Tarek S, Mahmoud Heba G M, Elshiwy Yasmine
Abstract excerpt
We investigated the association of the Osteopontin (OPN) (rs9138 and rs1126616) polymorphisms with colorectal cancer (CRC). One hundred CRC patients and 112 healthy individuals were subjected to OPN (rs9138 and rs1126616) genotyping and measurement of OPN protein plasma level. The C allele of OPN rs1126616 and the CC haplotype were significantly higher in CRC patient (p = 0.036, 0.003, respectively). In females,...
