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Article

Beta-2-adrenoreceptor polymorphism at position 16 determines the clinical severity of chronic obstructive pulmonary disease.

Pulmonary pharmacology & therapeutics - 1 Apr 2017

Emeryk-Maksymiuk Justyna, Emeryk Andrzej, Krawczyk Paweł, Wojas-Krawczyk Kamila, Milanowski Janusz

Abstract excerpt

The Arg/Arg homozygosity at codon 16 of the beta-2-adrenoreceptor (ADRB2) gene has been thought to predispose asthma patients to a poorer therapeutic response to beta-2-mimetics, or to worse control of the disease. In contrast, the results of the studies analysing the effect of ADRB2 polymorphisms on the response to beta-2-adrenoreceptor agonists in chronic obstructive pulmonary disease (COPD) patients are sparse...

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Source

Identifiers

PMID: 28093224
DOI: 10.1016/j.pupt.2017.01.005

Genes

ADRB2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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