Deregulated expression of VHL mRNA variants in papillary thyroid cancer.

doi:10.1016/j.mce.2017.01.019

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Deregulated expression of VHL mRNA variants in papillary thyroid cancer.

Molecular and cellular endocrinology - 5 Mar 2017

Baldini Enke, Tuccilli Chiara, Arlot-Bonnemains Yannick, Chesnel Frank, Sorrenti Salvatore, De Vito Corrado, Catania Antonio, D'Armiento Eleonora, Antonelli Alessandro, Fallahi Poupak, Watutantrige-Fernando Sara, Tartaglia Francesco, Barollo Susi, Mian Caterina, Bononi Marco, Arceri Stefano, Mascagni Domenico, Vergine Massimo, Pironi Daniele, Monti Massimo, Filippini Angelo, Ulisse Salvatore

Abstract excerpt

Recent findings demonstrated that a subset of papillary thyroid cancers (PTCs) is characterized by reduced expression of the von Hippel-Lindau (VHL) tumor suppressor gene, and that lowest levels associated with more aggressive PTCs. In the present study, the levels of the two VHL mRNA splicing variants, VHL-213 (V1) and VHL-172 (V2), were measured in a series of 96 PTC and corresponding normal matched tissues by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to Disease-Free Survival

Share to Kaplan-Meier Estimate

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Open in PubMed

Identifiers

PMID: 28089820
DOI: 10.1016/j.mce.2017.01.019

Genes

VHL
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Deregulated expression of VHL mRNA variants in papillary thyroid cancer.PMID 28089820Read ↗

Genome-Wide Expression Screening Discloses Long Noncoding RNAs Involved in Thyroid Carcinogenesis.Semantic proximity Read ↗

Significance of the BRAF mRNA Expression Level in Papillary Thyroid Carcinoma: An Analysis of The Cancer Genome Atlas Data.Semantic proximity Read ↗

Identification of Specific Long Non-Coding RNA Expression: Profile and Analysis of Association with Clinicopathologic Characteristics and BRAF Mutation in Papillary Thyroid Cancer.Semantic proximity Read ↗

Diagnostic accuracy in BRAF V600E-negative papillary thyroid cancer via 5-gene expression profiling of residual nucleic acids from mutation testing: a retrospective study.Semantic proximity Read ↗

BRAF<sup>V600E</sup> Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid CancerSemantic proximity Read ↗

Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker InvestigationsSemantic proximity Read ↗

Identification of Long Noncoding RNAs Deregulated in Papillary Thyroid Cancer and Correlated with BRAFV600E Mutation by Bioinformatics Integrative Analysis.Semantic proximity Read ↗

Functional loss of tumor suppressor genes detected by loss of heterozygosity, but not driver mutations, predicts aggressive lymph node status in papillary thyroid carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.