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Article

Environmental Deflection: The Impact of Toxicant Exposures on the Aging Epigenome.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Apr 2017

Kochmanski Joseph, Montrose Luke, Goodrich Jaclyn M, Dolinoy Dana C

Abstract excerpt

Epigenetic drift and age-related methylation have both been used in the literature to describe changes in DNA methylation that occurs with aging. However, ambiguity remains regarding the exact definition of both of these terms, and neither of these fields of study explicitly considers the impact of environmental factors on the aging epigenome. Recent twin studies have demonstrated longitudinal, pair-specific...

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Identifiers

PMID: 28087834
DOI: 10.1093/toxsci/kfx005
PMCID: PMC6256948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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