Article
Environmental Impact on DNA Methylation in the Germline: State of the Art and Gaps of Knowledge.
BioMed research international - 1 Jan 2015
Pacchierotti Francesca, Spanò Marcello
Abstract excerpt
The epigenome consists of chemical changes in DNA and chromatin that without modifying the DNA sequence modulate gene expression and cellular phenotype. The epigenome is highly plastic and reacts to changing external conditions with modifications that can be inherited to daughter cells and across generations. Whereas this innate plasticity allows for adaptation to a changing environment, it also implies the...
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