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Article

Donors FMO3 polymorphisms affect tacrolimus elimination in Chinese liver transplant patients.

Pharmacogenomics - 1 Feb 2017

Ren Lei, Teng Mujian, Zhang Tao, Zhang Xiaoqing, Sun Bo, Qin Shengying, Zhong Lin, Peng Zhihai, Fan Junwei

Abstract excerpt

AIM: Flavin-containing monooxygenase (FMO) variants were potentially involved in tacrolimus metabolism in kidney transplantion. The influences of FMO3 genotypes on tacrolimus elimination in Chinese liver transplant patients remained unclear. PATIENTS & METHODS: FMO3 SNPs and CYP3A5 rs776746 were analyzed in 110 Chinese patients. RESULTS: Donor FMO3 rs1800822 allele T and rs909530 allele T were associated with...

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Source

Identifiers

PMID: 28084894
DOI: 10.2217/pgs-2016-0098

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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