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Article

Single Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian.

Archivum immunologiae et therapiae experimentalis - 1 Dec 2016

Yao Yufeng, Wiśniewski Andrzej, Ma Qiangli, Kowal Aneta, Porębska Irena, Pawełczyk Konrad, Yu Jiankun, Dubis Joanna, Żuk Natalia, Li Yingfu, Shi Li, Kuśnierczyk Piotr

Abstract excerpt

An effective cytotoxic immune response to neoplastic cells requires efficient presentation of antigenic peptides to T lymphocytes by HLA class I (HLA-I) molecules. The HLA-I-bound peptide repertoire depends on antigen-processing machinery molecules. Aminopeptidase residing in endoplasmic reticulum 1 (ERAP1) trims peptides to the optimal length for HLA-I binding. Single nucleotide polymorphisms (SNPs) in the ERAP1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28083613
DOI: 10.1007/s00005-016-0436-4
PMCID: PMC5334393

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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