Article
The functional polymorphisms of LIS1 are associated with acute myeloid leukemia risk in a Han Chinese population.
Leukemia research - 1 Mar 2017
Cao Songyu, Lu Xiaomei, Wang Lihua, Qian Xifeng, Jin Guangfu, Ma Hongxia
Abstract excerpt
There is increasing evidence that the human lissencephaly-1 gene, LIS1, plays an important role in carcinogenesis of several malignancies including leukemia. However, little is known about the relationship between single nucleotide polymorphisms (SNPs) in LIS1 and the susceptibility to myeloid leukemia. In the present study, we systematically screened 5 potentially functional polymorphisms in LIS1, and conducted...
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