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Article

Dynamic change in the NS3 protease domain in HIV/HCV-coinfected patients naïve to anti-HCV protease inhibitors.

The new microbiologica - 1 Jan 2017

Bagaglio Simona, Messina Emanuela, Hasson Hamid, Merli Mario, Andolina Andrea, Lazzarin Adriano, Uberti-Foppa Caterina, Morsica Giulia

Abstract excerpt

The genetic analysis of THE natural protease inhibitors (PI) resistance of HCV genotype (GT)1 involves subtypes 1a and 1b. NS3 protease domain was sequentially analysed in 10 HIV/HCV GT1-coinfected individuals naïve to HCV treatment. Analysis at different time points showed that 2/3 GT1b patients were infected by a GT1a clade1 during follow-up. In one patient a switch from clade1 to clade2 and in one other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28072886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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