Article
TRIM-NHL proteins in development and disease.
Seminars in cell & developmental biology - 1 Dec 2015
Tocchini Cristina, Ciosk Rafal
Abstract excerpt
TRIM-NHL proteins are key regulators of developmental transitions, for example promoting differentiation, while inhibiting cell growth and proliferation, in stem and progenitor cells. Abnormalities in these proteins have been also associated with human diseases, particularly affecting muscular and neuronal functions, making them potential targets for therapeutic intervention. The purpose of this review is to...
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