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Article

TRIM21: a multifaceted regulator in cancer

15 Jul 2025

Abstract excerpt

Ubiquitination serves as a dynamic post-translational modification that enables rapid and precise regulation of cellular signaling networks. TRIM21, as an important member of the TRIM family, is a protein with E3 ubiquitin ligase activity. By specifically recognizing and ubiquitinating various substrate proteins, it plays a pivotal regulatory role in tumorigenesis and development. Moreover, TRIM21 has been found...

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PMID: 40735642
DOI: 10.3389/fcell.2025.1637451

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