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Article

RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations.

Journal of molecular biology - 27 Oct 2017

Laffleur Brice, Basu Uttiya, Lim Junghyun

Abstract excerpt

The eukaryotic RNA exosome is a well-conserved protein complex with ribonuclease activity implicated in RNA metabolism. Various families of non-coding RNAs have been identified as substrates of the complex, underscoring its role as a non-coding RNA processing/degradation unit. However, the role of RNA exosome and its RNA processing activity on DNA mutagenesis/alteration events have not been investigated until...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28069372
DOI: 10.1016/j.jmb.2016.12.021
PMCID: PMC5500447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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