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Article

Widespread Down-Regulation of Cardiac Mitochondrial and Sarcomeric Genes in Patients With Sepsis*

7 Jan 2017

Abstract excerpt

OBJECTIVES: The mechanism(s) for septic cardiomyopathy in humans is not known. To address this, we measured messenger RNA alterations in hearts from patients who died from systemic sepsis, in comparison to changed messenger RNA expression in nonfailing and failing human hearts. DESIGN: Identification of genes with altered abundance in septic cardiomyopathy, ischemic heart disease, or dilated cardiomyopathy, in...

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Share to Cardiomyopathy and Myosin Studies
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Identifiers

PMID: 28067713
DOI: 10.1097/ccm.0000000000002207

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