Article

Multimodal Analysis of Sepsis-induced Cardiomyopathy in a Baboon Model

2025-06-21

Abstract excerpt

Sepsis-induced cardiomyopathy (SIC) significantly contributes to sepsis-related morbidity and mortality, necessitating a deeper understanding of its mechanisms. This study used a post-hoc, multimodal approach—including single-nucleus RNA sequencing (snRNA-seq), echocardiography, mitochondrial function, and histopathology—to characterize SIC in a non-human primate model. Archived data and samples from six baboons c...

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Literature Corpus work: a6a17174-0fbd-5dd1-965f-6b5d9b06efe5
DOI: 10.1101/2025.06.16.659963

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