Article
Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression
5 Aug 2019
Abstract excerpt
Septic shock with heart dysfunction is very common in intensive care units. However, whether long noncoding RNA (lncRNA) and mRNA profiles differ between patients with and without myocardial depression is unknown. We generated rat models of hypodynamic septic shock induced by lipopolysaccharide. A total of 12 rat models was constructed and heart tissue from each was collected. Whole genomic RNA sequencing was...
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