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Article

Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study.

Scientific reports - 9 Jan 2017

Lin Honghuang, Yin Xiaoyan, Xie Zhijun, Lunetta Kathryn L, Lubitz Steven A, Larson Martin G, Ko Darae, Magnani Jared W, Mendelson Michael M, Liu Chunyu, McManus David D, Levy Daniel, Ellinor Patrick T, Benjamin Emelia J

Abstract excerpt

Atrial fibrillation (AF) is the most common cardiac arrhythmia, but little is known about the molecular mechanisms associated with AF arrhythmogenesis. DNA methylation is an important epigenetic mechanism that regulates gene expression and downstream biological processes. We hypothesize that DNA methylation might play an important role in the susceptibility to develop AF. A total of 2,639 participants from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28067321
DOI: 10.1038/srep40377
PMCID: PMC5220313

Genes

CUX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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