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Article

Association of Polymorphisms in three pri-miRNAs that Target Pepsinogen C with the Risk and Prognosis of Gastric Cancer.

Scientific reports - 9 Jan 2017

Wu Ye-Feng, Xu Qian, He Cai-Yun, Li Ying, Liu Jing-Wei, Deng Na, Sun Li-Ping, Yuan Yuan

Abstract excerpt

We aimed to explore the associations of polymorphisms in three microRNAs (miRNAs) (let-7e rs8111742, miR-365b rs121224 and miR-4795 rs1002765) that target PGC with the risk and prognosis of gastric cancer/atrophic gastritis. Sequenom's MassArray was used to genotype the miRNA polymorphisms in 724 gastric cancer cases, 862 atrophic gastritis cases and 862 controls in a Chinese population. We found that let-7e...

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Identifiers

PMID: 28067243
DOI: 10.1038/srep39528
PMCID: PMC5220333

Genes

PGC

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