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Article

A new polymorphism biomarker rs629367 associated with increased risk and poor survival of gastric cancer in chinese by up-regulated miRNA-let-7a expression.

PloS one - 1 Jan 2014

Xu Qian, Dong Qiguan, He Caiyun, Liu Wenjing, Sun Liping, Liu Jingwei, Xing Chengzhong, Li Xiaohang, Wang Bengang, Yuan Yuan

Abstract excerpt

BACKGROUND: Variant in pri-miRNA could affect miRNA expression and mature process or splicing efficiency, thus altering the hereditary susceptibility and prognosis of cancer. We aimed to assess miRNA-let-7 single nucleotide polymorphisms (SNP) associated with the risk and prognosis of gastric cancer (GC) as predicting biomarkers, and furthermore, its possible mechanisms. METHODS: A two-stage case-control study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24760009
DOI: 10.1371/journal.pone.0095249
PMCID: PMC3997364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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