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Article

Acidic pH with coordinated reduction of basic fibroblast growth factor maintains the glioblastoma stem cell-like phenotype in vitro.

Journal of bioscience and bioengineering - 1 May 2017

Haley Elizabeth M, Tilson Samantha G, Triantafillu Ursula L, Magrath Justin W, Kim Yonghyun

Abstract excerpt

Glioblastoma stem cells (GSCs) are a unique subpopulation of cells within glioblastoma multiforme (GBM) brain tumors that possess the ability to self-renew and differentiate into bulk tumor cells. GSCs are resistant to currently available treatments and are the likely culprit behind tumor relapse in GBM patients. However, GSCs are currently inaccessible to the larger scientific community because obtaining a...

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Source

Identifiers

PMID: 28063758
DOI: 10.1016/j.jbiosc.2016.12.006

Genes

GSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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