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Plant-derived human recombinant growth factors and serum albumin maintain stemness of human-induced pluripotent stem cells.

Cell biology international - 1 Jan 2022

Lee Yukyeong, Lee Hye Jeong, Ham Seokbeom, Jeong Dahee, Lee Minseong, Lee Uiil, Lee Myungseok, Kwon Tae-Ho, Ko Kinarm

Abstract excerpt

Stem cells are an important therapeutic source for recovery and regeneration, as their ability of self-renewal and differentiation offers an unlimited supply of highly specialized cells for therapeutic transplantation. Growth factors and serum are essential for maintaining the characteristics of stem cells in culture and for inducing differentiation. Because growth factors are produced mainly in bacterial...

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PMID: 34694043
DOI: 10.1002/cbin.11715
PMCID: PMC9298993

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