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GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System

7 Jul 2018

Abstract excerpt

Cell-based therapies hold great promise for a myriad of clinical applications. However, as these therapies move from phase I to phase II and III trials, there is a need to improve scale-up of adherent cells for the production of larger good manufacturing practice (GMP) cell banks. As we advanced our neural stem cell (NSC)-mediated gene therapy trials for glioma to include dose escalation and multiple treatment...

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PMID: 29992178
DOI: 10.1016/j.omtm.2018.05.006

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