Article
Regulation of chondrocyte functions by transient receptor potential cation channel V6 in osteoarthritis.
Journal of cellular physiology - 1 Nov 2017
Song Tengfei, Ma Jun, Guo Lei, Yang Peng, Zhou Xuhui, Ye Tianwen
Abstract excerpt
Transient receptor potential vanilloid (TRPV) channels function to maintain the dynamic balance of calcium signaling and calcium metabolism in bones. The goal of this study was to determine the potential role of TRPV6 in regulation of chondrocytes. The level of TRPV6 expression was analyzed by western blot in articular cartilage derived from the knee joints of osteoarthritis (OA) rat models and OA patients. Bone...
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