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Mycobacterium tuberculosis Complex Exhibits Lineage-Specific Variations Affecting Protein Ductility and Epitope Recognition.

Genome biology and evolution - 1 Dec 2016

Yruela Inmaculada, Contreras-Moreira Bruno, Magalhães Carlos, Osório Nuno S, Gonzalo-Asensio Jesús

Abstract excerpt

The advent of whole-genome sequencing has provided an unprecedented detail about the evolution and genetic significance of species-specific variations across the whole Mycobacterium tuberculosis Complex. However, little attention has been focused on understanding the functional roles of these variations in the protein coding sequences. In this work, we compare the coding sequences from 74 sequenced mycobacterial...

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Identifiers

PMID: 28062754
DOI: 10.1093/gbe/evw279
PMCID: PMC5521731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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