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Article

Regularly methylated novel pro‐apoptotic genes associated with recurrence in transitional cell carcinoma of the bladder

26 Apr 2006

Abstract excerpt

Epigenetic silencing of tumor suppressor genes by promoter hypermethylation has been shown for a variety of genes in bladder cancer. Various p53 target genes have been investigated, but only few demonstrated promoter hypermethylation when semiquantitative detection methods were applied. To address to the question whether promoter methylation of novel p53 effector genes is a common event in transitional cell...

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Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
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PMID: 16642478
DOI: 10.1002/ijc.21971

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