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Article

PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.

Molecular carcinogenesis - 1 Jul 2015

Dueñas Marta, Martínez-Fernández Mónica, García-Escudero Ramón, Villacampa Felipe, Marqués Miriam, Saiz-Ladera Cristina, Duarte José, Martínez Victor, Gómez M José, Martín M Luisa, Fernández Manoli, Castellano Daniel, Real Francisco X, Rodriguez-Peralto Jose L, De La Rosa Federico, Paramio Jesús M

Abstract excerpt

Bladder cancer (BC) is the fifth most common cancer in the world, being the non-muscle invasive tumors (NMIBC) the most frequent. NMIBC shows a very high frequency of recurrence and, in certain cases, tumor progression. The phosphatidylinositol 3-kinase (PI3K) pathway, which controls cell growth,...

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Identifiers

PMID: 24347284
DOI: 10.1002/mc.22125

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24347284-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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