Article
DNA Methylation profiles as predictors of recurrence in non muscle invasive bladder cancer: an MS-MLPA approach.
Journal of experimental & clinical cancer research : CR - 19 Nov 2013
Casadio Valentina, Molinari Chiara, Calistri Daniele, Tebaldi Michela, Gunelli Roberta, Serra Luigi, Falcini Fabio, Zingaretti Chiara, Silvestrini Rosella, Amadori Dino, Zoli Wainer
Abstract excerpt
BACKGROUND: Although non muscle invasive bladder cancer (NMIBC) generally has a good long-term prognosis, up to 80% of patients will nevertheless experience local recurrence after the primary tumor resection. The search for markers capable of accurately identifying patients at high risk of recurrence is ongoing. We retrospectively evaluated the methylation status of a panel of 24 tumor suppressor genes (TIMP3,...
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