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Article

Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease.

Scientific reports - 6 Jan 2017

Hao Jingcan, Wang Wenyu, Wen Yan, Xiao Xiao, He Awen, Wu Cuiyan, Wang Sen, Guo Xiong, Zhang Feng

Abstract excerpt

Kashin-Beck disease (KBD) is a chronic osteochondropathy. The pathogenesis of growth and development failure of hand of KBD remains elusive now. In this study, we conducted a two-stage genome-wide association study (GWAS) of palmar length-width ratio (LWR) of KBD, totally including 493 study subjects. Affymetrix Genome Wide Human SNP Array 6.0 was applied for genome-wide SNP genotyping of 90 KBD patients....

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Identifiers

PMID: 28059113
DOI: 10.1038/srep40020
PMCID: PMC5216336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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