Article
Heritability estimates and linkage analysis of 23 short tandem repeat loci on chromosomes 2, 11, and 12 in an endemic osteochondropathy in China.
Scandinavian journal of rheumatology - 1 May 2010
Shi X W, Guo X, Lv A L, Kang L, Zhou Y L, Zhang Y Z, Wu X M, Bai Y D
Abstract excerpt
OBJECTIVE: To estimate the heritability of Kashin-Beck disease (KBD) in first-degree relatives and to identify chromosome regions likely to contain susceptibility loci for KBD. METHODS: A total of 331 probands with confirmed KBD in their pedigrees were selected from 9331 residents in 17 KBD villages of Linyou county, northwestern China. The heritability (h(2)) in first-degree relatives was estimated by using...
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