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Article

AxGxE: Using Flies to Interrogate the Complex Etiology of Neurodegenerative Disease.

Current topics in developmental biology - 1 Jan 2017

Burke C, Trinh K, Nadar V, Sanyal S

Abstract excerpt

Progressive and late-onset neurological disorders such as Parkinson's disease and Alzheimer's disease affect up to 50 million people globally-a number postulated to double every 20 years in a continually aging population. While predisposing allelic variants in several genes clearly confer risk, individual age and specific environmental influences are equally important discriminators of disease onset age and...

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PMID: 28057301
DOI: 10.1016/bs.ctdb.2016.07.007

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