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Article

Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model.

BMC microbiology - 5 Jan 2017

Davies Emily V, James Chloe E, Brockhurst Michael A, Winstanley Craig

Abstract excerpt

BACKGROUND: During chronic lung infections of cystic fibrosis patients Pseudomonas aeruginosa populations undergo extensive evolutionary diversification. However, the selective drivers of this evolutionary process are poorly understood. To test the effects of temperate phages on diversification in P. aeruginosa biofilms we experimentally evolved populations of P. aeruginosa for approximately 240 generations in...

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Identifiers

PMID: 28056789
DOI: 10.1186/s12866-016-0916-z
PMCID: PMC5216580

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