Article
Evolutionary dynamics of bacteria in a human host environment.
Proceedings of the National Academy of Sciences of the United States of America - 3 May 2011
Yang Lei, Jelsbak Lars, Marvig Rasmus Lykke, Damkiær Søren, Workman Christopher T, Rau Martin Holm, Hansen Susse Kirkelund, Folkesson Anders, Johansen Helle Krogh, Ciofu Oana, Høiby Niels, Sommer Morten O A, Molin Søren
Abstract excerpt
Laboratory evolution experiments have led to important findings relating organism adaptation and genomic evolution. However, continuous monitoring of long-term evolution has been lacking for natural systems, limiting our understanding of these processes in situ. Here we characterize the evolutionary dynamics of a lineage of a clinically important opportunistic bacterial pathogen, Pseudomonas aeruginosa, as it...
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