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Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A Review

18 Aug 2014

Abstract excerpt

Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung disease. Its long persistence in CF airways is associated with sophisticated mechanisms of adaptation, including biofilm formation, resistance to antibiotics, hypermutability and customized pathogenicity in which virulence factors are expressed according the infection stage. CF adaptation is triggered by high selective pressure of...

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PMID: 25438018
DOI: 10.3390/pathogens3030680

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