Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation.

Immunology - 1 Nov 2017

Kästle Marc, Bartel Sabine, Geillinger-Kästle Kerstin, Irmler Martin, Beckers Johannes, Ryffel Bernhard, Eickelberg Oliver, Krauss-Etschmann Susanne

Abstract excerpt

T-helper cell type 17 (Th17) mediated inflammation is associated with various diseases including autoimmune encephalitis, inflammatory bowel disease and lung diseases such as chronic obstructive pulmonary disease and asthma. Differentiation into distinct T helper subtypes needs to be tightly regulated to ensure an immunological balance. As microRNAs (miRNAs) are critical regulators of signalling pathways, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Regulatory Networks
Share to Interleukin-17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to MicroRNAs

Share to Nuclear Receptor Subfamily 1, Group F, Member 1

Share to Nuclear Receptor Subfamily 1, Group F, Member 3

Share to Th17 Cells

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 28617945
DOI: 10.1111/imm.12775
PMCID: PMC5629441

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation.PMID 28617945Read ↗

miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune DiseasesSemantic proximity Read ↗

miR-141 and miR-200a are involved in Th17 cell differentiation by negatively regulating RARB expressionSemantic proximity Read ↗

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosisSemantic proximity Read ↗

MiRNA-374b-5p and miRNA-106a-5p are related to inflammatory bowel disease via regulating IL-10 and STAT3 signaling pathwaysSemantic proximity Read ↗

Genes associated with T helper 17 cell differentiation and functionSemantic proximity Read ↗

TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells.Semantic proximity Read ↗

Hsa-miR-374b-5p and hsa-miR-106a-5p are associated with inflammatory bowel disease through targeting IL-10/STAT3 axisSemantic proximity Read ↗

The role of microRNA-16 in the pathogenesis of autoimmune diseases: A comprehensive reviewSemantic proximity Read ↗

miRNA‐Regulated Key Components of Cytokine Signaling Pathways and Inflammation in Rheumatoid ArthritisSemantic proximity Read ↗

miR-20b Suppresses Th17 Differentiation and the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting RORγt and STAT3Semantic proximity Read ↗

MiR-9-5p and miR-106a-5p dysregulated in CD4+ T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation.Semantic proximity Read ↗

Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.