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Article

Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?

ILAR journal - 1 Dec 2016

Zuberi Aamir, Lutz Cathleen

Abstract excerpt

The use of mouse models in biomedical research and preclinical drug evaluation is on the rise. The advent of new molecular genome-altering technologies such as CRISPR/Cas9 allows for genetic mutations to be introduced into the germ line of a mouse faster and less expensively than previous methods. In addition, the rapid progress in the development and use of somatic transgenesis using viral vectors, as well as...

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Identifiers

PMID: 28053071
DOI: 10.1093/ilar/ilw021
PMCID: PMC5886322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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