Article
Effects of cytokine and cytokine receptor gene variation on high anti-HB titers: following up on Taiwan's neonatal hepatitis B immunization program.
Clinica chimica acta; international journal of clinical chemistry - 16 Aug 2012
Lin Ying-Ju, Lan Yu-Ching, Huang Yu-Chuen, Lin Ting-Hsu, Huang Shao-Mei, Lai Chien-Chen, Liu Chiu-Shong, Lin Cheng-Wen, Chen Shih-Yin, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: A significant percentage of Taiwanese neonatal HB immunization recipients have subsequently exhibited low anti-HB titers at non-protective or undetectable levels. Several mechanisms have been proposed to explain this phenomenon, including low vaccination responsiveness, deficient lymphocyte function, inappropriate antigen processing and presentation, and abnormal cytokine secretion. METHODS: To...
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