Article
IL28B SNP rs12979860 is the Critical Predictor for Sustained Viral Response in Chinese Children Aged 1 to 6 Years with Chronic Hepatitis C.
International journal of biological sciences - 1 Jan 2016
Zhong Yan-Wei, Zhang Hong-Fei, Shi Yan-Min, Li Yong-Li, Chu Fang, Xu Zhi-Qiang, Chen Da-Wei, Gan Yu, Wang Fu-Chuan, Gu Mei-Lei, Dong Yi, Zhu Shi-Shu, Shi Ce, Fan Hua-Hao, Zhang Xiu-Chang, Zhang Min
Abstract excerpt
Clinical data on children with chronic hepatitis C (CHC) remain extremely limited. This study investigated sustained virologic response (SVR) to alfa-interferon 2b plus RBV treatment in children aged 1-6 years with unsafe injection-acquired CHC. 154 children with CHC aged 1 to 6 years were enrolled, 101 of them were male (65.6%) and 53 were female (34.4%), and they were treated with alfa-interferon at a dose of...
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