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Article

Forkhead box a2 (FOXA2) is essential for uterine function and fertility

3 Jan 2017

Abstract excerpt

Establishment of pregnancy is a critical event, and failure of embryo implantation and stromal decidualization in the uterus contribute to significant numbers of pregnancy losses in women. Glands of the uterus are essential for establishment of pregnancy in mice and likely in humans. Forkhead box a2 (FOXA2) is a transcription factor expressed specifically in the glands of the uterus and is a critical regulator of...

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PMID: 28049832
DOI: 10.1073/pnas.1618433114

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