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Article

Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation.

British journal of clinical pharmacology - 1 Jun 2017

Calvo Pier Luigi, Serpe Loredana, Brunati Andrea, Nonnato Antonello, Bongioanni Daniela, Olio Dominic Dell', Pinon Michele, Ferretti Carlo, Tandoi Francesco, Carbonaro Giulia, Salizzoni Mauro, Amoroso Antonio, Romagnoli Renato, Canaparo Roberto

Abstract excerpt

AIM: The aim of the present study was to investigate the influence of the cytochrome P450 (CYP) 3A4/5 genotype in paediatric liver transplant recipients and donors, and the contribution of age and gender to tacrolimus disposition on the first day after transplantation. METHODS: The contribution of the CYP3A4/5 genotype in paediatric liver transplant recipients and donors to the tacrolimus blood trough...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28044353
DOI: 10.1111/bcp.13219
PMCID: PMC5427244

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